Which of the following factors is NOT associated with obesity-related cancer risk?

Stable metabolic rates are not associated with obesity-related cancer risk because they imply a balance in energy expenditure and intake, meaning that the body is not in a state of weight gain or loss. In contrast, obesity typically involves disrupted metabolic processes. Increased inflammation, altered hormone levels, and decreased physical activity are all significant contributors to the development of cancer in obese individuals.

Inflammation is a key factor because excess adipose tissue can produce inflammatory cytokines that promote cancer progression and development. Altered hormone levels, particularly elevated estrogen levels from fatty tissues, can influence the growth of hormone-sensitive cancers. Decreased physical activity has been directly linked to not only the development of obesity but also an increased cancer risk, as regular exercise is known to enhance metabolic health and possibly reduce cancer risk factors. Thus, the interplay of these factors contributes to an elevated cancer risk in those with obesity, while stable metabolic rates do not contribute to this risk.