What is the consequence of faulty checkpoints during the cell cycle?

Faulty checkpoints during the cell cycle can lead to a lack of proper regulation of cell division, which increases the risk of cells proliferating uncontrollably. These checkpoints are critical control points that monitor the integrity of the cell's DNA and ensure that conditions are suitable for division. When these checkpoints fail to function appropriately, cells may progress through the cell cycle despite having damaged DNA or other mutations, allowing abnormal cells to divide and accumulate.

This uncontrolled growth and division can ultimately lead to the development of cancer, as these mutated cells can evade normal growth controls, leading to tumor formation. Essentially, without the proper functioning of these checkpoints, the mechanisms that usually prevent potentially dangerous cells from dividing and proliferating are compromised, paving the way for cancerous growth.